Pd- d/e xk nuclease superfamily
Splet07. okt. 2016 · Kosinski J, Feder M, Bujnicki JM. The PD-(D/E)XK superfamily revisited: Identification of new members among proteins involved in DNA metabolism and functional predictions for domains of (hitherto) unknown function. BMC Bioinformatics. 2005; 6:172. doi: 10.1186/1471-2105-6-172; pmid: 16011798. [PMC free article] [Google Scholar] Splet12. jul. 2005 · BackgroundThe PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is one of the most challenging targets for protein sequence analysis and …
Pd- d/e xk nuclease superfamily
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Splet23. okt. 2024 · The Domain of unknown function 506 ( DUF506) family, which belongs to the PD- (D/E)XK nuclease superfamily, has not been functionally characterized. In this study, 266 DUF506 domain-containing genes were identified from algae, mosses, and land plants showing their wide occurrence in photosynthetic organisms. Splet27. jan. 2011 · Divalent metal ions are essential for the efficient catalysis and structural stability of many nucleotidyl-transfer enzymes. Poly(A)-specific ribonuclease (PARN) belongs to the DEDD superfamily of 3'-exonucleases, and the active site of PARN contains four conserved acidic amino acid residues that coordinate two Mg2+ ions. In this …
Splet24. maj 2012 · The PD-(D/E)XK phosphodiesterases span over 21 900 proteins, which can be classified into 121 groups of various families. Eleven of them, including DUF4420, … Splet06. feb. 2009 · The primary evolutionary advantage for the PD-(D/E)XK nuclease superfamily is its stable and multifunctional core fold, which orients catalytic residues in optimal geometry for a phosphoryl transfer reaction while providing a highly adaptable surrounding scaffold that can easily accommodate additional structural elaborations. …
Splet12. jul. 2005 · The PD- (D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is … Splet23. okt. 2024 · The Domain of unknown function 506 (DUF506) family, which belongs to the PD-(D/E)XK nuclease superfamily, has not been functionally characterized. In this study, …
Splet20. jun. 2007 · Restriction endonuclease-like proteins, also called a PD- (D/E)XK nucleases, constitute a large and diverse superfamily of enzymes that are involved in numerous …
Splet12. jul. 2005 · The PD- (D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is one of the most challenging targets for protein sequence analysis and structure prediction. lineman school grand junctionSplet01. feb. 2001 · The PD- (D/E)XK nuclease domains, initially identified in type II restriction enzymes, serve as models for studying aspects of protein-DNA interactions, mechanisms … lineman school in alliance nebraskaSpletThe PD-(D/E)XK nuclease domains, initially identified in type II restriction enzymes, serve as models for studying aspects of protein-DNA interactions, mechanisms of phosphodiester … lineman school idaho fallsSpletThe PD-(D/E)XK nuclease domains, initially identified in type II restriction enzymes, serve as models for ... degree of amino acid conservation hampers the possibility of identification of PD-(D/E)XK superfamily members based solely on sequence comparisons. In several proteins implicated in DNA recombination and repair the restriction enzyme ... hotsy burner partsSplet12. jul. 2007 · These results are in very good agreement with the structural model presented in this work and with our prediction that R.Eco29kI belongs to the GIY-YIG superfamily of nucleases. Our study provides the first experimental evidence for a Type IIP REase that does not belong to the PD- (D/E)XK or HNH superfamilies of nucleases, and is instead a ... hotsy burner assemblySpletthe PD(D/E)XK nuclease superfamily. This is possibly due to multiple steric constraints placed on the compact HNH motif, which is simultaneously involved in protein folding, DNA binding, and catalysis, as well as the use of a planar, aromatic imidazole group … hotsy bismarck ndSplet08. mar. 2024 · The presence of this motif suggests that Hna belongs to the PD- (D/E)XK nuclease SF, which comprises a diverse group of proteins with a variety of cellular functions. 28 The overall domain organization of Hna thus appears similar to the Res subunit of type III restriction endonucleases such as Eco P1I, in which a C-terminal … hotsy burner troubleshooting