Line1 orf1 antibody
Nettet17. okt. 2024 · Uhrf1 ablation in male germ cell leads to retrotransposon activation. a RT-qPCR analysis of the expression of retrotransposon ( Line1, IAP ), DNA transposon (MusD), peri-centromeric repeats... Nettettestis sections of the indicated genotypes are shown. The exposure is set to detect L1 Orf1 expression in MiliCtl tubules, note both MiliC-KO and MiliC-DAH tubules are overexposed at these settings. (F) Immunofluorescence using anti-L1 Orf1 and anti-γH2AX antibodies on adult testis sections of the indicated genotypes are shown.
Line1 orf1 antibody
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NettetHas reverse transcriptase activity required for target-primed reverse transcription of the LINE-1 element mRNA, a crucial step in LINE-1 retrotransposition (PubMed:9140393, … NettetAntibodies that detect L1/ORF2 can be used in several scientific applications, including ELISA and Western Blot. These antibodies target L1/ORF2 in Mouse, Human and …
NettetBackground The L1 (LINE-1), or Long INterspersed Element , retrotransposon ORF2 is the most common open reading frame in the human genome, present in various forms in many thousands of copies. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signaling. NettetLINE1-ORF 1P serves as a nucleic acid-binding protein that is essential for retrotransposition of LINE-1 elements in the genome. It is also reported to function as a …
NettetAnti-LINE-1 ORF1p Antibody, clone 4H1 Detect LINE-1 retrotransposable element ORF1 protein using this mouse monoclonal Anti-LINE-1 ORF1p Anibody, clone 4H1, Cat. No. MABC1152. It is used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, and Western Blotting. - Find MSDS or SDS, a COA, data sheets …
NettetAnti-LINE-1 ORF1p Antibody, clone 4H1 clone 4H1, from mouse; Synonyms: LINE-1 retrotransposable element ORF1 protein, L1ORF1p, LINE retrotransposable element 1, …
Nettet结果: 制备的line1-orf1p抗体效价 > 1:16 000,能对细胞及肿瘤组织内line1-orf1p特异识别。转染pegfp-n1-line1-orf1的wt_cls1细胞,其line1-orf1的mrna及蛋白水平显著增高(p … fun outdoor preschool activities for summerNettetBy evaluating the expression of LINE1 elements, it was found that high levels of ORF1 occur more frequently in breast and ovarian cancer (Chen et al., 2012; Rodic et al., … github 8iosafriNettet31. des. 2024 · To test whether ORF2p could be detected with specific reagents, we developed and validated five rabbit monoclonal antibodies with immunoreactivity for … fun outdoor things to do at homeNettet1. jun. 2024 · The LINE1-ORF1p antibody prepared had a titer of >1:16 000 and could specifically recognize LINE1-ORF1p in cells and tumor tissue. WT_CLS1 cells … fun outdoor summer gamesNettetThe first ORF of L1 encodes a 500-amino acid, 40- kDa protein that lacks homology with any protein of known function. In vertebrates, it contains a conserved C-terminus domain and a highly variable coiled-coil N-terminus that … fun outdoor thermometerNettet25. jun. 2004 · LINE-1 (long interspersed nuclear element) retrotransposons (L1) 1 cover about 17% of the human genome ( 1) and play a significant role in shaping the mammalian genome, not only through their own expansion but … github 900hasseNettetAnti-LINE-1 ORF1p Antibody, clone 4H1 Detect LINE-1 retrotransposable element ORF1 protein using this mouse monoclonal Anti-LINE-1 ORF1p Anibody, clone 4H1, Cat. No. … fun outdoor summer activities for kids