Immunity-related gtpase family m protein 1
Witryna4 kwi 2024 · immunity-related GTPase family M member 2. Synonyms. Gtpi, Iigp2 Feature Type. protein coding gene. IDs. MGI:1926262 ... protein coding gene: Chr11:58090444-58113609 (+) 129S1/SvImJ: MGP_129S1SvImJ_G0018346: protein coding gene: Chr11:57879087-57906842 (+) A/J: MGP_AJ_G0018316: Witryna4 kwi 2024 · Related ENSP00000428220.1, ENST00000522154.2 Conserved Domains (1) summary cl21455 Location: 33 → 180 P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases; NM_001346557.2 → NP_001333486.1 immunity-related GTPase family M protein isoform 1. Status: REVIEWED. Source sequence(s) …
Immunity-related gtpase family m protein 1
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Witryna13 kwi 2024 · immunity-related GTPase family M protein. ISC. intestinal stem cell. LC3. microtubule-associated protein 1A/1B-light chain 3. LPS. lipopolysaccharide. LRRK. leucine-rich repeat serine/threonine-protein kinase 1. MTMR. myotubularin phosphatase. mTOR. mammalian target of rapamycin. MUC2 mucin 2. Witryna6 kwi 2024 · Ran binding protein 1 (RanBP1), which is expressed between eukaryotes and vertebrates, but not in some invertebrate species such as flies and worms, is a Ran-GTP-binding protein [].It is a co-activator of the Ran-GTPase activating protein, RanGAP1 [].RanBP1 plays a role in Ran-dependent nucleocytoplasmic transport …
Witryna13 kwi 2024 · Fujimoto, M. et al. CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification. Immunity 13 , 47–57 (2000). Article CAS PubMed Google Scholar WitrynaThe prototypical DOCK protein, DOCK180, is an evolutionarily conserved Rac regulator and is indispensable during processes such as cell migration and myoblast fusion. The biological activity of DOCK180 is tightly linked to its binding partner ELMO. We previously reported that autoinhibited ELMO proteins regulate signaling from this pathway.
Witryna6 maj 2011 · Here, we examined a complete mouse 65-kilodalton (kD) guanylate-binding protein (Gbp) gene family as part of a 43-member IFN-γ–inducible guanosine triphosphatase (GTPase) superfamily in mouse and human genomes. Family-wide loss-of-function analysis found that at least four Gbps—Gbp1, Gbp6, Gbp7, and … Witryna21 kwi 2014 · The data suggest that palmitoylation together with the αK helix firmly anchor Irgm1 in the Golgi and mitochondria, thus facilitating function of the protein. The Immunity-Related GTPases (IRG) are a family of large GTPases that mediate innate immune responses. Irgm1 is particularly critical for immunity to bacteria and …
Witryna12 kwi 2024 · Metastasis, the leading cause of cancer-related death in patients diagnosed with ovarian cancer (OC), is a complex process that involves multiple biological effects. With the continuous development of sequencing technology, single-cell sequence has emerged as a promising strategy to understand the pathogenesis of …
Immunity-related GTPase family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is encoded by the IRGM gene. IRGM is a member of the interferon-inducible GTPase family. The encoded protein may play a role in the innate immune response by regulating … Zobacz więcej Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Zobacz więcej • Laukens D, Georges M, Libioulle C, Sandor C, Mni M, Vander Cruyssen B, et al. (November 2010). "Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis" Zobacz więcej graph network visualizationWitryna10 kwi 2024 · RhoA is a small GTPase in the Rho family and is involved in several cellular processes, including cell proliferation and differentiation. ... Our results showed that DSS treatment leads to decreased levels of the tight junction proteins, ZO-1 and occludin, in Caco-2 cells and increased levels of RhoA, ROCK1, and ROCK2; … graph networkx pythonWitrynaLenti ORF particles, IRGM (Myc-DDK-tagged)-Human immunity-related GTPase family, M (IRGM), 200ul, >10^7 TU/mL Supplier Page. Supplier Page from OriGene Technologies for IRGM (NM_001145805) Human Tagged ORF Clone Lentiviral Particle. Product Specs; Company Info; Reviews; Product Specs; graph neural diffusion with a source termWitryna2 wrz 2011 · The immunity-related GTPases (IRGs) are a family of proteins induced by interferon-γ that play a crucial role in innate resistance to intracellular pathogens. The M subfamily of IRG proteins (IRGM) plays a profound role in this context, in part because of the ability of its members to regulate the localization and expression of … graph network theoryWitrynaThe IRGM gene provides instructions for making a protein that plays an important role in the immune system. This protein is involved in a process called autophagy, which cells use to surround and destroy foreign invaders such as bacteria and viruses. ... M; immunity-related GTPase family, M1; immunity-related GTPase M; IRGM1; LRG … chisholm trail end crossword clueWitrynaThe classic G-protein heterotrimer consists of three subunits: one Gα, one Gβ and one Gγ. The Gα protein is a catalytically active GTPase and, in its active conformation, interacts with downstream effectors to transduce signals. Gα proteins across the plant evolutionary lineage show a high degree of sequence conservation. graph network transfer learningWitrynaThere are 20 Rho GTPases in the human genome, including Rac1 and Cdc42, which have a deep impact on cell proliferation, differentiation, motility, adhesion, survival and secretion. 42 As Rho GTPase activators, DOCK proteins were first identified as exchange factors for Rac1/2/3 and Cdc42 more than 10 years ago. 16 Thus, the … chisholm trail end crossword