WebConnective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature … WebOct 21, 2010 · Connective tissue growth factor (CTGF, also known as CCN2 [Cyr61/CTGF/NOV]) is a profibrotic growth factor that induces proliferation of vascular smooth muscle cells and accumulation of extracellular matrix by …
Connective Tissue Growth Factor - an overview
WebSep 15, 2024 · Background Malignant mesothelioma (MM) is an aggressive mesothelial cell cancer type linked mainly to asbestos inhalation. MM characterizes by rapid progression and resistance to standard therapeutic modalities such as surgery, chemotherapy, and radiotherapy. Our previous studies have suggested that tumor cell-derived connective … WebAug 9, 2012 · What is a CGF file? 3D model format used by CryENGINE, a 3D game engine; created using the 3D application included with the CryENGINE SDK; contains … orchestrated pronunciation
CTGF regulates cell proliferation, migration, and glucose …
WebApr 30, 2016 · ERK1/2 acts on connective tissue growth factor (CTGF/CCN2) expression to mediate the myocardial fibrosis and left ventricular dysfunction. Studies in vivo demonstrate that inhibiting CTGF/CCN2 using a specific antibody decreases myocardial fibrosis and improves the left ventricular dysfunction. Together, these findings show that … WebMay 1, 2007 · The tissue repair process is regulated by a number of polypeptides including cytokines and growth factors. Connective tissue growth factor (CTGF) is a 38-kDa cysteine-rich polypeptide that was originally identified from conditioned medium of human umbilical vein endothelial cells (HUVECs) ().CTGF, considered to be a downstream … WebDec 1, 2003 · Connective tissue growth factor (CTGF) has been described as a growth factor that acts downstream of TGF-β in the fibrotic process ().However, TGF-β–independent induction of CTGF has also been described (12–14).It has been demonstrated that CTGF is induced in mesangial cells under hyperglycemic conditions, … ipv6wry.db